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Another type of prescription weight loss drug is a fat absorption inhibitor. Xenical is th

e only example of this type of treatment approved for use in the U.S. Xenical works by blocking about 30% of dietary fat from being absorbed, and is the most recently approved weight loss drug. Meridia and Xenical are the only weight-loss medications approved for longer-term use in significantly obese people, although the safety and effectiveness have not been established for use beyond 2 years.

Obesity often requires long-term treatment to promote and sustain weight loss. As in other chronic conditions, such as diabetes or high blood pressure, use of prescription medications may be appropriate for some people. While most side effects of prescription medications for obesity are mild, seriou

Most available weight-loss medications are "appetite-suppressant" medications. These include: Didrex, Tenuate, Sanorex, Mazanor, Adipex-P, Ionamin, Bontril and Meridia. These medications generally come in the form of tablets or extended-release capsules (pills that release medication over a long period of time). Appetite suppressants can be obtained by a doctor's prescription or purchased over the counter.

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In general, Xenical and Meridia are moderately effective, leading to an average weight loss of 5 to 22 pounds over a 1-year period, more than what would be expected with non-drug treatments. However, the response to these medications is based on each individual, and some people experience more weight loss than others. Likewise, there is no one correct dose for these medications.

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