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There are two basic types of weight loss drugs -- prescription drugs, which have been around for years, and now, with the release of Alli, over-the-counter medication. Other over-the-counter weight loss remedies are considered dietary supplements; they do not undergo the same type of FDA approval process as drugs.
Xenical (orlistat) is a fat blocker that prevents fat from being completely absorbed in the gastrointestinal tract. Prescription strength is 120 milligrams; over-the-counter Alli is the same drug at half strength, or 60 milligrams. Fat blockers reduce fat absorption and, as a result, some people are
"Approved weight loss drugs must prove they are safe and effective with strong scientific evidence in order to pass the stringent FDA approval process," says Aronne, former president of the North American Association for the Study of Obesity (NAASO). In the prescription drug category, there are basically three choices, Xenical (orlistat), Meridia (sibutramine), and phentermine.
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Phentermine is generic, the least expensive of the medications, and has been on the market the longest. Once a part of the famed fen-phen combination weight loss drug, Phentermine works to decrease appetite. It is the most widely used weight loss drug. While it's officially approved only as a short-term drug, some doctors use it as long term therapy.
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