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BMRs
BMRs are not the whole story relating weight and thyroid. For example, when metabolic rates are reduced in animals by various means, these animals often do not show the expected excess weight gain. Thus, the relationship between metabolic rates, energy balance, and weight changes is very complex. There are many other hormones, proteins, and other chemicals that are very important for controlling energy expenditure, food intake, and body weight.
Taking more thyroid hormone might help him lose weight but much of the weight loss will be protein and he will increase his risks for osteoporosis and heart problems. In addition taking too much thyroid hormone may make it even more difficult for him to lose weight if the dose of thyroxine is decrea
It has been appreciated for a very long time that there is a complex relationship between thyroid disease, body weight and metabolism. Thyroid hormone regulates metabolism in both animals and humans. Metabolism is determined by measuring the amount of oxygen used by the body over a specific amount of time. If the measurement is made at rest, it is known as the basal metabolic rate (BMR).
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Indeed, measurement of the BMR was one of the earliest tests used to assess a patient's thyroid status. Patients whose thyroid glands were not working were found to have low BMRs, and those with overactive thyroid glands had high BMRs. Later studies linked these observations with measurements of thyroid hormone levels and showed that low thyroid hormone levels were associated with low BMRs and high thyroid hormone levels were associated with BMRs.
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